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About the Team


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Stephen B. Howell, M.D.

Stephen B. Howell, M.D. is a medical oncologist and Distinguished Professor of Medicine at the University of California, San Diego. He is a graduate of Harvard Medical School and was trained as a medical oncologist and pharmacologist at the Massachusetts General Hospital, the National Institutes of Health and the Dana Farber Cancer Institute. Dr. Howell is head of Laboratory of Pharmacology at the Moores Cancer Center. He is past director of the Cancer Therapeutics Training Program and the co-head of the Solid Tumor Therapeutics Program of the Cancer Center. His work focuses on the development of novel drugs and drug delivery systems for the treatment of cancer. He is the author of more than 370 peer-reviewed research articles. Dr. Howell conducted much of the early pharmacokinetic studies and clinical trials work on intraperitoneal chemotherapy for the treatment of ovarian cancer. His laboratory has contributed importantly to the current understanding of how the platinum-containing drugs enter, traffic through and exit from ovarian cancer cells, and how such cells become resistant to these drugs.

  • Maria Carmen Mulero, Ph.D.

    Maria Carmen Mulero, Ph.D.

    Maria Mulero Roig, PhD (Project Scientist III) is an expert protein chemist with extensive experience in the purification and analysis of difficult proteins and investigation of their roles in normal and malignant cells.

  • Dennis Gately, Ph.D.

    Dennis Gately, Ph.D.

    Dennis Gately, PhD (Visiting Scientist) has had a career in the field of antibody-drug conjugates and is an expert in the design, production, and testing of novel protein therapeutics.

  • Himangshu Sonowal, Ph.D.

    Himangshu Sonowal, Ph.D.

    Himangshu Sonowal, PhD (Project Scientist II) is trained in experimental therapeutics including the analysis of mechanisms of action of existing and novel anti-cancer drugs and the changes that occur during the development of resistance.

  • Erika Barth, M.S.

    Erika Barth, M.S.

    Erika Barth, MS (Staff Research Associate II) is the Manager of the Howell lab. She has experience in the cell and molecular biology techniques used in the production and purification of recombinant protein drugs, and in vitro testing of their function and cytoxicity.

  • Clara Wong, M.S.

    Clara Wong, M.S.

    Clara Wong, BS (Staff Research Associate I) is a cell and molecular biologist with experience in experimental therapeutics including both in vitro and in vivo techniques for assessment of purity, cytotoxicity and in efficacy. 

  • Cathy Rice, B.S.

    Cathy Rice, B.S.

    Catherine Rice, BS (Volunteer) has extensive experience in the field of experimental therapeutics and drug development and is an expert in cell biologic analytic techniques of novel protein therapeutics.

  • Alex Lin

    Alex Lin

  • Mindy Nguyen

    Mindy Nguyen

  • Owen Tai

    Owen Tai