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Cancer Biology and Signaling

CANCER BIOLOGY
AND SIGNALING

The Cancer Biology and Signaling program conducts basic research on the biological processes that underlie normal cell growth regulation and the initiation and progression of cancer.

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RUNX2 promotes fibrosis via an alveolar-to-pathological fibroblast transition

Particle uptake by macrophages triggers bifurcated transcriptional pathways that differentially regulate inflammation and lysosomal gene expression

Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2

Inside the Lab: Researcher Spotlight with J. Silvio Gutkind, PhD