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Research Programs

Cancer Biology and Signaling

Membership Resources

As a member you will be connected with researchers across the cancer continuum, from basic science through public health, and across all UCSD schools, SDSU and La Jolla institute. Learn more about funding opportunities and other member resources today.

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Upcoming events, lectures & seminars


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Recent Program Publications

Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer.

Nature Communications

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aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete β-arrestin-2-mediated Sphk1-S1PR1-Akt signaling axis

Proceedings of the National Academy of Sciences of the United States of American

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Strength of immune selection in tumors varies with sex and age

Nature Communications

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Speed Mentor Workshop

Opportunity for trainees and junior faculty to network and ask questions about career paths, scientific progress, and learning healthcare organizational culture

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Rob Signer, PhD

Assistant Professor
Department of Medicine
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Colleen McHugh, PhD

Assistant Professor
Department of Chemistry and Biochemistry
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David Schlaepfer, PhD

Professor
Department of OBGYN and Reproductive Sciences

May 12

12-1pm on Zoom


upcoming dates

Sep 8

Oct 13

Nov 10

Dec 8

CT2 Lecture Series

Training the next generation of leaders in cancer drug and diagnostics development

Mondays 12PM - 1PM VIA ZOOM

3/14/22

Development of an Individualized Neoantigen Cancer Vaccine

Speaker: Erza Cohen, M.D.

3/21/22

Comparative Effectiveness of Immune Checkpoint Inhibitors vs. Chemotherapy by Tumor Mutational Burden in Metastatic Prostate Cancer: Filling Evidence Gaps using Real-World Data

Speaker: Ryan Graf, PhD

5/23/22

Macrophage mediated antibody targeting of drug resistant solid tumors

Stephen McCormack, PhD, Alpha Beta Therapeutics

Zoom link: https://uchealth.zoom.us/j/81843764035?pwd=pdpFtTQTNsS2uY1NscOtjWYWS1mnep.1
Password: 673134

Overview

The Cancer Biology and Signaling Program (CBS) conducts basic research on the biological processes that underlie normal cell growth regulation and the initiation and progression of cancer.  Learn more about the program and goals here

Overview

 

Leadership

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JING YANG, Ph.D.

Professor of Pharmacology and Pediatrics
Moores Cancer Center

Phone: 858-534-1994
Email: jiyang@ucsd.edu

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KUN-LIANG GUAN, PH.D.

Distinguished Professor of Pharmacology
Moores Cancer Center

Email: kuguan@ucsd.edu