Skip to main content
styles - DO NOT REMOVE

Shared Resources

Biorepository and Tissue Technology

OVERVIEW

Availability of high-quality, annotated human tissue specimens and comprehensive histopathological services at  the College of American Pathologists (CAP) - accredited UC San Diego Biorepository and Tissue Technology Shared Resources (BTTSR)

The BTTSR is founded on a well-established model that integrates tissue procurement, processing, storage, and  multimodal (histologic, immunohistochemical, and molecular) analyses with traditional epidemiologic, clinicopathologic,  and outcome parameters through a highly evolved bioinformatics system.  

The mission of the BTTSR is to support MCC, C3, and outside researchers’ projects by providing annotated human bio- specimens, and state-of-the-art histology processing, interpretation, and histopathological analysis of samples. 


 

Services

We provide a wide range of services

Biorepository Services

  • Patient consenting​
  • Tissue acquisition​
    • Prospective collection ​
    • Clinical trial support​
  • Tissue storage ​
  • Distribution ​
    • Blood derivatives: Buffy Coat, Plasma, Serum, PBMC ​
    • Fresh Frozen Tissue: neoplastic and non-neoplastic ​
    • Viable freeze  ​
    • Formalin fixed paraffin embedded  Tissue: neoplastic& non-neoplastic ​
    • Formalin fixed paraffin embedded  Tissue: Autopsy ​
    • PDX Models ​
  • Other services ​
    • DNA and RNA Extraction and QA 
  • Fill out a Request Form for Biorepository Services

Contact Information:

Sharmeela Kaushal
Biorepository Assistant Director
skaushal@health.ucsd.edu
Office: (858) 534-7302

Tissue Technology Services

  • Routine Histology​
    • Tissue processing and sectioning  (formalin fixed and frozen tissue)​
    • Routine H&E and specialized staining ​
  • Immunohistochemistry/Immunofluorescence​
    • Antibody optimization and validation​
    • Single and multiplexing detection assays ​
  • Whole slide scanning​
    • Brightfield AT2 Aperio​
    • Fluorescent (up to 6 channels + DAPI) PhenoImager Akoya​
  • Phenocycler Fusion: Ultra-plex Imaging​
  • Customized Tissue Micro Array (TMA) ​
  • Experimental pathology consultation​​
  • Click here to request services: https://redcap.link/TTSRRequestForm-HistologyServices

Contact Information:​

M. Valeria Estrada​
Tissue Technology Assistant Director​
mvestrada@health.ucsd.edu

Office: (858) 534-8607

Recharge Rates

​Item Description

Measurable Unit

MCC Member Cost

C3 Cost

UCSD (Non-MCC Member) Cost

Industry Rate

Ascites (Fresh)

per case

$55

$64

$72

$123

Assay Handling

per hour

$50

$58

$65

$110

Block Storage / year

per block

$7

$8

$9

$14

Buffy Coat (250 uL)

per aliquot

$39

$46

$51

$87

Cell Count Assay / sample

per cassette

$4

$5

$5

$8

DNA or RNA Extraction (All Tissue Types)

per sample

$49

$57

$64

$109

Frozen Section

per section

$5

$6

$7

$11

Frozen Tissue, Embedding

per OCT block

$7

$8

$9

$15

IHC Optimization

per antibody

$195

$226

$254

$431

IRB Usage & Preparation/One-Time/PI

each

$812

$942

$1,056

$1,789

Miscellaneous

per unit

$100

$116

$130

$221

Paraffin Block

per block

$6

$7

$7

$11

Paraffin Section

per slide

$5

$6

$7

$12

Pathology Consultation Fee

per hour

$285

$330

$371

$628

PBMC (1 mL)

per aliquot

$55

$63

$72

$121

Plasma or Serum (500 uL)

per aliquot

$11

$13

$14

$24

RNA/DNA + QA for Omics/Assay (12 Samples)

per cassette

$115

$133

$150

$254

Routine Stain

per slide

$4

$5

$5

$8

Saliva

each

$40

$47

$52

$89

SOP Development

each

$525

$608

$683

$1,157

Special Stain

per slide

$15

$18

$20

$34

Storage - Liquid (-80º) or LN2 per month

per box

$20

$23

$26

$45

Tech Time

per hour

$120

$139

$156

$264

Tissue Print/Aliquot

each

$170

$197

$221

$374

Urine (500 uL)

per aliquot

$11

$13

$14

$23

Viable Fresh Frozen Tissue

each

$308

$357

$400

$677

Whole Blood/Case

per tube

$81

$94

$105

$179

Xenografted Viable Freeze Tumor (PDX)

each

$150

$174

$195

$330

Antibody Aliquot/Slide

each

$5

$6

$7

$12

Aperio Scanning (20X)

per slide

$10

$12

$13

$22

Aperio Scanning (40X)

per slide

$15

$18

$20

$33

Ascites Processing

per tube

$70

$81

$91

$154

Buffy Coat Processing

per tube

$70

$81

$91

$155

Cassettes

per 10 units

$10

$12

$10

$17

Cassette Labeling/Grossing

per cassette

$3

$3

$3

$6

Cytospin Use

per slide

$4

$4

$5

$8

Decalcification

per order

$10

$12

$10

$18

Delivery Fee

per round trip

$12

$14

$12

$21

IF Scanning (20X)

per slide

$30

$35

$39

$66

IF Scanning (40X)

per slide

$40

$46

$52

$87

IHC/IF Staining (Primary Antibody not included)

per slide

$30

$35

$39

$66

Large Slide Box

per unit

$7

$9

$9

$15

Multiplexing IF (2 markers + DAPI)

per slide

$60

$69

$78

$133

Multiplexing IF (3 markers + DAPI)

per slide

$90

$1014

$117

$197

Multiplexing IF (4 markers + DAPI)

per slide

$120

$139

$156

$264

Multiplexing IF (5 markers + DAPI)

per slide

$150

$174

$195

$330

Multiplexing IF (6 markers + DAPI)

per slide

$180

$208

$234

$396

Paraffin Block Access

per block

$75

$87

$98

$166

Pathologist's Assistant Time

per hour

$150

$174

$195

$331

PBMC Processing

per tube

$135

$157

$176

$299

Phenocycler Assay - Base Cost (Antibodies not included)

per slide

$2,000

$2,319

$2,000

$3,387

Plasma or Serum Processing

per tube

$70

$81

$91

$154

Rush Processing Fee

per unit

$100

$116

$130

$220

Scrolls (3 scrolls at 10-20 um)

per block

$10

$12

$13

$22

Slide Labeling

per slide

$1

$1

$1

$1

Small Slide Box

per unit

$5

$5

$5

$5

Solid Fresh Frozen Tissue (50 mg)

per aliquot

$95

$110

$124

$210

Solid Fresh Tissue Collection (Biopsy - FFPE Processing)

per block

$7

$8

$9

$16

Solid Fresh Tissue Collection (Biopsy - OCT Processing)

per block

$70

$81

$91

$154

Solid Fresh Tissue Collection (Biopsy)

each

$120

$139

$156

$265

Solid Fresh Tissue Collection (Surgical)

each

$274

$318

$356

$602

Storage - Liquid (-80º) / per month, per Shelf

per shelf

$30

$34

$39

$65

Storage - Liquid (-80º) / per month, per Freezer

per freezer

$100

$116

$130

$220

TMA / Core

each

$5

$6

$7

$12

TMA - Case Identification

per hour

$74

$85

$95

$160

TMA Unstained slides/24 core TMA/Slide

per slide

$50

$58

$65

$110

TMA Unstained slides/48 core TMA/Slide

per slide

$70

$82

$91

$155