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PREDICT Initiative

Groundbreaking advances in molecular science, imaging and artificial intelligence are making it possible to detect cancer at its earliest stages, often before symptoms even appear.

The PREDICT Initiative (Prevention, Risk Assessment, Early Detection and Interception of Cancer through Technology) is here to meet this moment: bringing world-class clinical care together with innovative research in molecular science, data science, and AI, moving discoveries from the lab into real-world patient care.

Early Detection Saves Lives

40% of people will be diagnosed with cancer in their lifetime

Nearly 50% of cancers are found at later stages

Many cancers can be prevented

PREDICT Initiative Pillars 

PREDICT rests on five interconnected pillars, each designed to close a gap in how we detect, understand, and ultimately prevent cancer: 

Pillar 01: High-risk screening clinics, Pillar 02: unified data and AI Analytics, Pillar 03: Early Onset Cancer Research, Pillar 04: Environmental Risk Research, Pillar 05: One Million San Diegans Screened

 

Pillar 1: High-Risk Screening Clinics

Advancing genomic testing, risk-based screening, and specialized clinical diagnostics for patients and families

Pillar 2: Unified Data and AI Analytics

Consolidating UC Health System EHR data with AI-driven analytics to uncover shared causes, parallels, and personalized therapies

Pillar 3: Early-Onset Cancer Resarch

Investigating the rising incidence of cancer in younger adults to identify emerging risk factors and biological mechanisms

Pillar 4: Environmental Risk Research

Examining environmental and exposure-related factors that contribute to cancer incidence across San Diego communities

Pillar 5: One Million San Diegans Screened

Delivering cancer screening at population scale across the greater San Diego region
Headshot of Diane Simeone, MD

Message from the Director

We now have the scientific tools to see cancer earlier than ever before, sometimes years before a tumor would show up on a scan. That's not a distant possibility. It's happening in labs and clinics today. Our job through the PREDICT Initiative is to take that science and put it directly into the hands of physicians and patients, as fast and as responsibly as we can.

Leadership

Headshot for Dr. Alexandrov

Ludmil Alexandrov, PhD

Scientific Director

Headshot for Dr. Gupta

Samir Gupta, MD

Clinical Director

Headshot for Dr. Aran

Kiana Aran, PhD

Technology Director

Our Guiding Principles

Rigor

Every tool we develop is tested and validated to the highest scientific standards

Access

Early detection must work for everyone. We evaluate our tools across all patient populations

Translation

Research only matters if it reaches patients. Every program has a clear path to clinical care

Collaboration

No one institution can solve this alone. We partner across UC campuses and with institutions nationally and globally

 

Join Us 

Whether you're a patient, a physician, or a potential collaborator, there's a place for you in this work. Learn more about our research programs, refer a patient, or partner with us to help bring earlier cancer detection to more people, faster.

 

CONTACT US