MICROSCOPY PUBLICATIONS

Select publications, 2002–2023:

Arang N, Lubrano S, Ceribelli M, Rigiracciolo DC, Saddawi-Konefka R, Faraji F, Ramirez SI, Kim D, Tosto FA, Stevenson E, Zhou Y, Wang Z, Bogomolovas J, Molinolo AA, Swaney DL, Krogan NJ, Yang J, Coma S, Pachter JA, Aplin AE, Alessi DR, Thomas CJ, Gutkind JS. High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma. Cell Rep Med. 2023 Nov 21;4(11):101244. doi:10.1016/j.xcrm.2023.101244. Epub 2023 Oct 18. PMID: 37858338; PMCID: PMC10694608.

Bukhari M, Patel N, Fontana R, Santiago-Medina M, Jiang Y, Li D, Pestonjamasp K, Christiansen VJ, Jackson KW, McKee PA, Yang J. Fibroblast activation protein drives tumor metastasis via a protease-independent role in invadopodia stabilization. Cell Rep. 2023 Oct 31;42(10):113302. doi: 10.1016/j.celrep.2023.113302. Epub 2023 Oct 19. PMID: 37862167; PMCID: PMC10742343.

Krishnan N, Jiang Y, Zhou J, Mohapatra A, Peng FX, Duan Y, Holay M, Chekuri S, Guo Z, Gao W, Fang RH, Zhang L. A modular approach to enhancing cell membrane-coated nanoparticle functionality using genetic engineering. Nat Nanotechnol. 2023 Oct 30. doi: 10.1038/s41565-023-01533-w. Epub ahead of print. PMID: 37903891.

Chung YH, Ortega-Rivera OA, Volckaert BA, Jung E, Zhao Z, Steinmetz NF. Viral nanoparticle vaccines against S100A9 reduce lung tumor seeding and metastasis. Proc Natl Acad Sci U S A. 2023 Oct 24;120(43):e2221859120. doi: 10.1073/pnas.2221859120. Epub 2023 Oct 16. PMID: 37844250; PMCID: PMC10614828.5: Jung E, Chung YH, Steinmetz NF. TLR Agonists Delivered by Plant Virus and Bacteriophage Nanoparticles for Cancer Immunotherapy. Bioconjug Chem. 2023 Sep 20;34(9):1596-1605. doi: 10.1021/acs.bioconjchem.3c00271. Epub 2023 Aug 23. PMID: 37611278; PMCID: PMC10538388.

Gulay KCM, Zhang X, Pantazopoulou V, Patel J, Esparza E, Pran Babu DS, Ogawa S, Weitz J, Ng I, Mose ES, Pu M, Engle DD, Lowy AM, Tiriac H. Dual Inhibition of KRASG12D and Pan-ERBB Is Synergistic in Pancreatic Ductal Adenocarcinoma. Cancer Res. 2023 Sep 15;83(18):3001-3012. doi: 10.1158/0008-5472.CAN-23-1313. PMID: 37378556; PMCID: PMC10502451.

Guo Z, Noh I, Zhu AT, Yu Y, Gao W, Fang RH, Zhang L. Cancer Cell Membrane Nanodiscs for Antitumor Vaccination. Nano Lett. 2023 Sep 13;23(17):7941-7949. doi: 0.1021/acs.nanolett.3c01775. Epub 2023 Aug 21. PMID: 37602707; PMCID: PMC10542934.

Duan Y, Zhang E, Fang RH, Gao W, Zhang L. Capsulated Cellular Nanosponges for the Treatment of Experimental Inflammatory Bowel Disease. ACS Nano. 2023 Aug 22;17(16):15893-15904. doi: 10.1021/acsnano.3c03959. Epub 2023 Aug 11. PMID: 37565604.

Rohila D, Park IH, Pham TV, Weitz J, Hurtado de Mendoza T, Madheswaran S, Ishfaq M, Beaman C, Tapia E, Sun S, Patel J, Tamayo P, Lowy AM, Joshi S. Syk Inhibition Reprograms Tumor-Associated Macrophages and Overcomes Gemcitabine-Induced Immunosuppression in Pancreatic Ductal Adenocarcinoma. Cancer Res. 2023 Aug 15;83(16):2675-2689. doi: 10.1158/0008-5472.CAN-22-3645. PMID: 37306759; PMCID: PMC10416758.

1Weitz J, Garg B, Martsinkovskiy A, Patel S, Tiriac H, Lowy AM. Pancreatic ductal adenocarcinoma induces neural injury that promotes a transcriptomic and functional repair signature by peripheral neuroglia. Oncogene. 2023 Aug;42(34):2536-2546. doi: 10.1038/s41388-023-02775-7. Epub 2023 Jul 11. PMID: 37433986.

Weitz J, Garg B, Tiriac H, Martsinkovskiy A, Patel S, Lowy A. Pancreatic Ductal Adenocarcinoma Induces Neural Injury that Promotes a Transcriptomic and Functional Repair Signature by peripheral Neuroglia. Res Sq [Preprint]. 2023 Mar 28:rs.3.rs-2715023. doi: 10.21203/rs.3.rs-2715023/v1. Update in: Oncogene. 2023 Jul 11;: PMID: 37034696; PMCID: PMC10081383.

Zhao Z, Ortega-Rivera OA, Chung YH, Simms A, Steinmetz NF. A co-formulated vaccine of irradiated cancer cells and cowpea mosaic virus improves ovarian cancer rejection. J Mater Chem B. 2023 Jun 21;11(24):5429-5441. doi: 10.1039/d2tb02355e. PMID: 36861401; PMCID: PMC10293063.

Dong T, Shah JR, Phung AT, Larson C, Sanchez AB, Aisagbonhi O, Blair SL, Oronsky B, Trogler WC, Reid T, Kummel AC. A Local and Abscopal Effect Observed with Liposomal Encapsulation of Intratumorally Injected Oncolytic Adenoviral Therapy. Cancers (Basel). 2023 Jun 12;15(12):3157. doi: 10.3390/cancers15123157. PMID: 37370769; PMCID: PMC10296131.

Chua BA, Lennan CJ, Sunshine MJ, Dreifke D, Chawla A, Bennett EJ, Signer RAJ. Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis. Cell Stem Cell. 2023 Apr 6;30(4):460-472.e6. doi: 10.1016/j.stem.2023.02.010. Epub 2023 Mar 21. PMID: 36948186; PMCID: PMC10164413.

Arimoto KI, Miyauchi S, Troutman TD, Zhang Y, Liu M, Stoner SA, Davis AG, Fan JB, Huang YJ, Yan M, Glass CK, Zhang DE. Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis. Nat Commun. 2023 Jan 17;14(1):251. doi: 10.1038/s41467-022-35348-5. PMID: 36646704; PMCID: PMC9842760.

Rohila D, Park IH, Pham TV, Jones R, Tapia E, Liu KX, Tamayo P, Yu A, Sharabi AB, Joshi S. Targeting macrophage Syk enhances responses to immune checkpoint blockade and radiotherapy in high-risk neuroblastoma. Front Immunol. 2023 Jun 7;14:1148317. doi: 10.3389/fimmu.2023.1148317. PMID: 37350973; PMCID: PMC10283071.

Hurtado de Mendoza T, Mose ES, Botta GP, Braun GB, Kotamraju VR, French RP, Suzuki K, Miyamura N, Teesalu T, Ruoslahti E, Lowy AM, Sugahara KN. Tumor-penetrating therapy for β5 integrin-rich pancreas cancer. Nat Commun. 2021 Mar 9;12(1):1541. doi: 10.1038/s41467-021-21858-1. PMID: 33750829; PMCID: PMC7943581.

Weitz J, Garg B, Martsinkovskiy A, Patel S, Tiriac H, Lowy AM. Pancreatic ductal adenocarcinoma induces neural injury that promotes a transcriptomic and functional repair signature by peripheral neuroglia. Oncogene. 2023 Aug;42(34):2536-2546. doi: 10.1038/s41388-023-02775-7. Epub 2023 Jul 11. PMID: 37433986.

Zhivagui M, Hoda A, Valenzuela N, Yeh YY, Dai J, He Y, Nandi SP, Otlu B, Van Houten B, Alexandrov LB. DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer. Nat Commun. 2023 Jan 17;14(1):276. doi: 10.1038/s41467-023-35876-8. Erratum in: Nat Commun. 2023 Mar 14;14(1):1424. doi: 10.1038/s41467-023-37245-x. PMID: 36650165; PMCID: PMC9845303.

Weitz J, Montecillo Gulay KC, Hurtado de Mendoza T, Tiriac H, Baumgartner J, Kelly K, Veerapong J, Lowy AM. Culture and Imaging of Ex Vivo Organotypic Pseudomyxoma Peritonei Tumor Slices from Resected Human Tumor Specimens. J Vis Exp. 2022 Dec 9;(190). doi: 10.3791/64620. PMID: 36571414.

Ozmadenci D, Shankara Narayanan JS, Andrew J, Ojalill M, Barrie AM, Jiang S, Iyer S, Chen XL, Rose M, Estrada V, Molinolo A, Bertotto T, Mikulski Z, McHale MC, White RR, Connolly DC, Pachter JA, Kuchroo VK, Stupack DG, Schlaepfer DD. Tumor FAK orchestrates immunosuppression in ovarian cancer via the CD155/TIGIT axis. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2117065119. doi: 10.1073/pnas.2117065119. Epub 2022 Apr 25. PMID: 35467979; PMCID: PMC9169934.

Chung YH, Volckaert BA, Steinmetz NF. Metastatic Colon Cancer Treatment Using S100A9-Targeted Cowpea Mosaic Virus Nanoparticles. Biomacromolecules. 2022 Dec 12;23(12):5127-5136. doi: 10.1021/acs.biomac.2c00873. Epub 2022 Nov 14. PMID: 36375170; PMCID: PMC9772157.

Affonso de Oliveira JF, Chan SK, Omole AO, Agrawal V, Steinmetz NF. In Vivo Fate of Cowpea Mosaic Virus In Situ Vaccine: Biodistribution and Clearance. ACS nano. 2022 Nov 22;16(11):18315-18328. doi: 10.1021/acsnano.2c06143. Epub 2022 Oct 20. PMID: 36264973; PMCID: PMC9840517.

Weitz J, Hurtado de Mendoza T, Tiriac H, Lee J, Sun S, Garg B, Patel J, Li K, Baumgartner J, Kelly KJ, Veerapong J, Hosseini M, Chen Y, Lowy AM. An Ex Vivo Organotypic Culture Platform for Functional Interrogation of Human Appendiceal Cancer Reveals a Prominent and Heterogenous Immunological Landscape. Clin Cancer Res. 2022 Nov 1;28(21):4793-4806. doi: 10.1158/1078-0432.CCR-22-0980. PMID: 36067351.

Sun Q, Wang Y, Officer A, Pecknold B, Lee G, Harismendy O, Desgrosellier JS. Stem-like breast cancer cells in the activated state resist genetic stress via TGFBI-ZEB1. NPJ Breast Cancer. 2022 Jan 13;8(1):5. doi: 10.1038/s41523-021-00375-w. PMID: 35027548; PMCID: PMC8758745.

Nkanga CI, Steinmetz NF. Injectable Hydrogel Containing Cowpea Mosaic Virus Nanoparticles Prevents Colon Cancer Growth. ACS Biomater Sci Eng. 2022 Jun 13;8(6):2518-2525. doi: 10.1021/acsbiomaterials.2c00284. Epub 2022 May 6. PMID: 35522951; PMCID: PMC9840516.

Koellhoffer EC, Mao C, Beiss V, Wang L, Fiering SN, Boone CE, Steinmetz NF. Inactivated Cowpea Mosaic Virus in Combination with OX40 Agonist Primes Potent Antitumor Immunity in a Bilateral Melanoma Mouse Model. Mol Pharm. 2022 Feb 7;19(2):592-601. doi: 10.1021/acs.molpharmaceut.1c00681. Epub 2022 Jan 3. PMID: 34978197; PMCID: PMC9207558.

Li P, Li Q, Biswas N, Xin H, Diemer T, Liu L, Perez Gutierrez L, Paternostro G, Piermarocchi C, Domanskyi S, Wang RK, Ferrara N. LIF, a mitogen for choroidal endothelial cells, protects the choriocapillaris: implications for prevention of geographic atrophy. EMBO Mol Med. 2022 Jan 11;14(1):e14511. doi: 10.15252/emmm.202114511. Epub 2021 Nov 15. PMID: 34779136; PMCID: PMC8749470.

Park JH, Mohapatra A, Zhou J, Holay M, Krishnan N, Gao W, Fang RH, Zhang L. Virus-Mimicking Cell Membrane-Coated Nanoparticles for Cytosolic Delivery of mRNA. Angew Chem Int Ed Engl. 2022 Jan 10;61(2):e202113671. doi: 10.1002/anie.202113671. Epub 2021 Nov 29. PMID: 34694684; PMCID: PMC8727555.

Weitz JR, Tiriac H, Hurtado de Mendoza T, Wascher A, Lowy AM. Using Organotypic Tissue Slices to Investigate the Microenvironment of Pancreatic Cancer: Pharmacotyping and Beyond. Cancers (Basel). 2021 Oct 5;13(19):4991. doi: 10.3390/cancers13194991. PMID: 34638476; PMCID: PMC8507648.

Zhou J, Karshalev E, Mundaca-Uribe R, Esteban-Fernández de Ávila B, Krishnan N, Xiao C, Ventura CJ, Gong H, Zhang Q, Gao W, Fang RH, Wang J, Zhang L. Physical Disruption of Solid Tumors by Immunostimulatory Microrobots Enhances Antitumor Immunity. Adv Mater. 2021 Dec;33(49):e2103505. doi: 10.1002/adma.202103505. Epub 2021 Oct 11. PMID: 34599770; PMCID: PMC8975929.

Boone CE, Wang C, Lopez-Ramirez MA, Beiss V, Shukla S, Chariou PL, Kupor D, Rueda R, Wang J, Steinmetz NF. Active Microneedle Administration of Plant Virus Nanoparticles for Cancer <i>in situ</i> Vaccination Improves Immunotherapeutic Efficacy. ACS Appl Nano Mater. 2020 Aug 28;3(8):8037-8051. doi: 10.1021/acsanm.0c01506. Epub 2020 Aug 7. PMID: 33969278; PMCID: PMC8101548.

Lee S, Burner DN, Mendoza TR, Muldong MT, Arreola C, Wu CN, Cacalano NA, Kulidjian AA, Kane CJ, Jamieson CAM. Establishment and Analysis of Three-Dimensional (3D) Organoids Derived from Patient Prostate Cancer Bone Metastasis Specimens and their Xenografts. J Vis Exp. 2020 Feb 3;(156). doi: 10.3791/60367. PMID: 32065165.

Patel BK, Wang C, Lorens B, Levine AD, Steinmetz NF, Shukla S. Cowpea Mosaic Virus (CPMV)-Based Cancer Testis Antigen NY-ESO-1 Vaccine Elicits an Antigen-Specific Cytotoxic T Cell Response. ACS Appl Bio Mater. 2020 Jul 20;3(7):4179-4187. doi: 10.1021/acsabm.0c00259. Epub 2020 Jun 25. PMID: 34368641; PMCID: PMC8340627.

Diaz Osterman CJ, Ozmadenci D, Kleinschmidt EG, Taylor KN, Barrie AM, Jiang S, Bean LM, Sulzmaier FJ, Jean C, Tancioni I, Anderson K, Uryu S, Cordasco EA, Li J, Chen XL, Fu G, Ojalill M, Rappu P, Heino J, Mark AM, Xu G, Fisch KM, Kolev VN, Weaver DT, Pachter JA, Győrffy B, McHale MT, Connolly DC, Molinolo A, Stupack DG, Schlaepfer DD. FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy. Elife. 2019 Sep 3;8:e47327. doi: 10.7554/eLife.47327. PMID: 31478830; PMCID: PMC6721800.

Reilly SM,Hung CW, Ahmadian M, Zhao P, Keinan O, Gomez AV, DeLuca JH, Dadpey B, Lu D, Zaid J, Poirier B, Peng X, Yu RT, Downes M, Liddle C, Evans RM.,Murphy AN, Saltiel AR. Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3. Nature Metabolism 2020 Jun;2522-5812.
doi.org/10.1038/s42255-020-0217-6

Chen W, Barback CV, Wang S, Hoh CK, Chang EY, Hall DJ, Head BP, Vera DR. Type I receptor-binding radiopharmaceutical for imaging of traumatic brain injury in arodent model:[99mTc] Tc-tilmanocept. Nucl Med Biol. 2020 Mar 5:S0969-8051(20)30003-2. doi: 10.1016/j.nucmedbio.2020.02.013.

Fan JB, Miyauchi S, Xu HZ, Liu D, Kim LJY, Burkart C, Cheng H, Arimoto KI, Yan M, Zhou Y, Győrffy B, Knobeloch KP, Rich JN, Cang H, Fu XD, Zhang DEInterferon Regulates a Coordinated Gene Network to Enhance Cytotoxic T Cell-Mediated Tumor Killing. Cancer Discov. 2020 Mar;10(3):382-393. doi:10.1158/2159-8290.CD-19-0608.

Hingorani DV, Doan MK, Camargo MF, Aguilera J, Song SM, Pizzo D, Scanderbeg, DJ, Cohen EEW, Lowy AM, Adams SR, Advani SJ. Precision Chemoradiotherapy for HER2 Tumors Using Antibody Conjugates of an Auristatin Derivative with Reduced Cell Permeability. Mol Cancer Ther. 2020 Jan;19(1):157-167. doi: 10.1158/1535-7163.MCT-18-1302.

Hingorani DV, Crisp JL, Doan MK, Camargo MF, Quraishi MA, Aguilera J, Gilardi M, Gross LA, Jiang T, Li WT, Ongkeko WM, Cohen EEW, Gutkind JS, Adams SR, Advani SJ. Redirecting extracellular proteases to molecularly guide radiosensitizing drugs to tumors. Biomaterials. 2020 Jul;248:120032. doi:10.1016/j.biomaterials.2020.120032.

Banerjee S, Yoon H, Yebra M, Tang CM, Gilardi M, Shankara Narayanan JS, White RR, Sicklick JK, Ray P. Anti-KIT DNA Aptamer for Targeted Labeling of Gastrointestinal Stromal Tumor. Mol Cancer Ther. 2020 May;19(5):1173-1182. doi: 10.1158/1535-7163.MCT-19-0959.

Sun, Q, Wang, Y, and Desgrosellier, JS. (2019). Combined Bcl-2/Src inhibition synergize to deplete stem-like breast cancer cells. Cancer Letters 457, 40-46. DOI:10.1016/j.canlet.2019.05.004

Wang S, Zhang Z, Almenar-Queralt A, Leem J, DerMardirossian C, Roth DM, Patel PM, Patel HH, Head BP. Caveolin-1 Phosphorylation Is Essential for Axonal Growthof Human Neurons Derived From iPSCs. Front Cell Neurosci. 2019 Jul 17;13:324. doi: 10.3389/fncel.2019.00324.

Sawada A, Wang S, Jian M, Leem J, Wackerbarth J, Egawa J, Schilling JM, Platoshyn O, Zemljic-Harpf A, Roth DM, Patel HH, Patel PM, Marsala M, Head BP. Neuron-targeted caveolin-1 improves neuromuscular function and extends survival in SOD1^G93A mice. FASEB J. 2019 Jun;33(6):7545-7554. doi:10.1096/fj.201802652RR.

Chekuri A, Zientara-Rytter K, Soto-Hermida A, Borooah S, Voronchikhina M, Biswas P, Kumar V, Goodsell D, Hayward C, Shaw P, Stanton C, Garland D,Subramani S, Ayyagari R. Late-onset retinal degeneration pathology due to
mutations in CTRP5 is mediated through HTRA1. Aging Cell. 2019 Dec;18(6):e13011. doi: 10.1111/acel.13011.

Qin Z, Hoh CK, Olson ES, Jahromi AH, Hall DJ, Barback CV, You YH, Yanagita M, Sharma K, Vera DR. Molecular Imaging of the Glomerulus via Mesangial Cell Uptakeof Radiolabeled Tilmanocept. J Nucl Med. 2019 Sep;60(9):1325-1332. doi: 10.2967/jnumed.118.223727.

Chekuri A, Sahu B, Chavali VRM, Voronchikhina M, Soto-Hermida A, Suk JJ, Alapati AN, Bartsch DU, Ayala-Ramirez R, Zenteno JC, Dinculescu A, Jablonski MM,Borooah S, Ayyagari R. Long-Term Effects of Gene Therapy in a Novel Mouse Model of Human MFRP-Associated Retinopathy. Hum Gene Ther. 2019 May;30(5):632-650.
doi: 10.1089/hum.2018.192.

Hertel F, Mo GCH, Dedecker P, Zhang J. Observing the Assembly of Protein Complexes in Living Eukaryotic Cells in Super-Resolution Using refSOFI. MethodsMol Biol. 2018;1764:267-277. doi: 10.1007/978-1-4939-7759-8_16.

Chekuri A, Guru AA, Biswas P, Branham K, Borooah S, Soto-Hermida A, Hicks M, Khan NW, Matsui H, Alapati A, Raghavendra PB, Roosing S, Sarangapani S, Mathavan S, Telenti A, Heckenlively JR, Riazuddin SA, Frazer KA, Sieving PA, Ayyagari R. IFT88 mutations identified in individuals with non-syndromic recessive retinal degeneration result in abnormal ciliogenesis. Hum Genet. 2018 Jul;137(6-7):447-458. doi: 10.1007/s00439-018-1897-9.

Biswas P, Duncan JL, Ali M, Matsui H, Naeem MA, Raghavendra PB, Frazer KA, Arts HH, Riazuddin S, Akram J, Hejtmancik JF, Riazuddin SA, Ayyagari R. A mutation in IFT43 causes non-syndromic recessive retinal degeneration. Hum Mol Genet. 2017 Dec 1;26(23):4741-4751. doi: 10.1093/hmg/ddx356.

Mo GC, Ross B, Hertel F, Manna P, Yang X, Greenwald E, Booth C, Plummer AM, Tenner B, Chen Z, Wang Y, Kennedy EJ, Cole PA, Fleming KG, Palmer A, Jimenez R, Xiao J, Dedecker P, Zhang J. Genetically encoded biosensors for visualizing live-cell biochemical activity at super-resolution. Nat Methods. 2017 Apr;14(4):427-434. doi: 10.1038/nmeth.4221.

Ungerleider JL, J. K. KammeyerJK, Braden RL, Christman KL Gianneschi NC. Enzyme-targeted nanoparticles for delivery to ischemic skeletal muscle. Polym. Chem. 2017; 8: 5212.

Mo GCH, Ross B, Hertel F, Manna P, Yang X, Greenwald E, Booth C, Plummer AM, Tenner B, Chen Z, Wang Y, Kennedy EJ, Cole PA, Fleming KG, Palmer A, Jimenez R, Xi J, Dedecker P, Zhang J. Genetically encoded biosensors for visualizing live-cell biochemical activity at super-resolution. Nature Methods. 2017 April;14:427- 434

Lin KC, Moroishi T, Meng Z, Jeong H-S, Plouffe SW, Sekido Y, Han J, Park HW, Guan KL. Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation. Nat Cell Biol. 2017 Jul 28;19(8):996–1002.

Batova A, Altomare D, Creek KE, Naviaux RK, Wang L, Li K, Green E, Williams R, Naviaux JC, Diccianni M, Yu AL. Englerin A induces an acute inflammatory response and reveals lipid metabolism and ER stress as targetable vulnerabilities in renal cell carcinoma. PLoS One. 2017; 12(3): e0172632.

Yu J, Chen L, Chen Y, Hasan MK, Ghia EM, Zhang L, Wu R, Rassenti LZ, Widhopf GF, Shen Z, Briggs SP, Kipps TJ. Wnt5a induces ROR1 to associate with 14-3-3ζ for enhanced chemotaxis and proliferation of chronic lymphocytic leukemia cells. Leukemia. 2017 Dec; 31(12): 2608–2614.

Hasan MK, Yu J, Chen L, Cui B, Widhopf Ii GF, Rassenti L, Shen Z, Briggs SP, Kipps TJ. Wnt5a induces ROR1 to complex with HS1 to enhance migration of chronic lymphocytic leukemia cells. Leukemia. 2017 May 31(12).

Zhu Y, Gong K, Denholtz M, Chandra V, Kamps MP, Alber F, Murre C. Comprehensive characterization of neutrophil genome topology. Genes Dev. 2017 Jan 15;31(2):141-153.

Adams SR, Yang HC, Savariar EN, Aguilera J, Crisp JL, Jones KA, Whitney MA, Lippman SM, Cohen EEW, Tsien RY, Advani SJ, Anti-tubulin drugs conjugated to anti-ErbB antibodies selectively radiosensitize. Nature Communications. 2016 Oct;7:13019-13029

Chakedis J, French R, Babicky M, Jaquish D, Howard H, Mose E, Lam R, Holman P, Miyamoto J, Walterscheid Z, Lowy AM. A novel protein isoform of the RON tyrosine kinase receptor transforms human pancreatic duct epithelial cells. Oncogene. 2016 Jun 23;35(25):3249-59.

Yu J, Chen L, Cui B, Widhopf GF 2nd, Shen Z, Wu R, Zhang L, Zhang S, Briggs SP, Kipps TJ. Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferation. J Clin Invest. 2016 Feb;126(2):585-98.

Krishna KM, Aznar N, Laederich B, Ma GS, Kunkel MT, Newton A,Ghosh P. Multimodular biosensors reveal a novel platform for activation of G proteins by growth factor receptors. Proc. Natl. Acad. Sci. U S A. 2015 March;112:937-946

Shang X, Lin X, Howell SB . Claudin-4 controls the receptor tyrosine kinase EphA2 pro-oncogenic switch through ß-catenin. Cell Commun Signal. 2014 Oct 25;12:59.

Tsai CY, Larson CA, Safaei R, Howell SB. Molecular modulation of the copper and cisplatin transport function of CTR1 and its interaction with IRS-4. Biochem Pharmacol. 2014 Aug 15;90(4):379-87.

Godebu E, Muldong M, Strasner A, Wu CN, Park SC, Woo JR, Ma W, Liss MA, Hirata T, Raheem O, Catalina NA, Kulidjian AA, Jamieson CA. PCSD1, a new patient-derived model of bone metastatic prostate cancer, is castrate-resistant in the bone-niche. J Transl Med. 2014 Oct 3;12:275.

Zhang S, Cui B, Lai H, Liu G, Ghia EM, Widhopf GF 2nd, Zhang Z, Wu CC, Chen L, Wu R, Schwab R, Carson DA, Kipps TJ. Ovarian cancer stem cells express ROR1, which can be targeted for anti-cancer-stem-cell therapy. Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17266-71.

Shi G, Cui W, Benchimol M, Liu YT, Mattrey RF, Mukthavaram R, Kesari S, Esener SC, Simberg D. Isolation of rare tumor cells from blood cells with buoyant immuno-microbubbles. PLoS One. 2013;8(3):e58017.

Lu M, Sarruf DA, Li P, Osborn O, Sanchez-Alavez M, Talukdar S, Chen A, Bandyopadhyay G, Xu J, Morinaga H, Dines K, Watkins S, Kaiyala K, Schwartz MW, Olefsky JM. Neuronal Sirt1 deficiency increases insulin sensitivity in both brain and peripheral tissues. J Biol Chem. 2013 Apr 12;288(15):10722-35.

Sen S, Jumaa H, Webster NJ. Splicing factor SRSF3 is crucial for hepatocyte differentiation and metabolic function. Nat Commun. 2013;4:1336. Tsai JH, Donaher JL, Murphy DA, Chau S, Yang J. Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis. Cancer Cell. 2012 Dec 11;22(6):725-36.

Kopp JL, von Figura G, Mayes E, Liu FF, Dubois CL, Morris JP 4th, Pan FC, Akiyama H, Wright CV, Jensen K, Hebrok M, Sander M. Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma. Cancer Cell. 2012 Dec 11;22(6):737-50.

Jacques BE, Puligilla C, Weichert RM, Ferrer-Vaquer A, Hadjantonakis AK, Kelley MW, Dabdoub A. A dual function for canonical Wnt/β-catenin signaling in the developing mammalian cochlea. Development. 2012 Dec 1;139(23):4395-404.

Shang X, Lin X, Alvarez E, Manorek G, Howell SB. Tight junction proteins claudin-3 and claudin-4 control tumor growth and metastases. Neoplasia. 2012 Oct;14(10):974-85.

Hu Q, Tanasa B, Trabucchi M, Li W, Zhang J, Ohgi KA, Rose DW, Glass CK, Rosenfeld MG. DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation. Nat Struct Mol Biol. 2012 Nov;19(11):1168-75.

Lin YC, Benner C, Mansson R, Heinz S, Miyazaki K, Miyazaki M, Chandra V, Bossen C, Glass CK, Murre C. Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate. Nat Immunol. 2012 Dec;13(12):1196-204.

Hayashi T, Yao S, Crain B, Chan M, Tawatao RI, Gray C, Vuong L, Lao F, Cottam HB, Carson DA, Corr M. Treatment of autoimmune inflammation by a TLR7 ligand regulating the innate immune system. PLoS One. 2012;7(9):e45860.

Lee JH, Budanov AV, Talukdar S, Park EJ, Park HL, Park HW, Bandyopadhyay G, Li N, Aghajan M, Jang I, Wolfe AM, Perkins GA, Ellisman MH, Bier E, Scadeng M, Foretz M, Viollet B, Olefsky J, Karin M. Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3. Cell Metab. 2012 Sep 5;16(3):311-21.

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