STT SCIENTIFIC HIGHLIGHTS

Recent Scientific Highlights from Solid Tumor Therapeutics Research Program members. Please contact us if you have a highlight to share.

Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis

Zhe Zhu, Pinar Mesci, Jean A. Bernatchez, Ryan C. Gimple, Xiuxing Wang, Simon T. Schafer, Hiromi I. Wettersten, Sungjun Beck, Alex E. Clark, Qiulian Wu, Briana C. Prager, Leo J.Y. Kim, Rekha Dhanwani, Sonia Sharma, Alexandra Garancher, Sara M. Weis, Stephen C. Mack, Priscilla D. Negraes, Cleber A. Trujillo, Luiz O. Penalva, Jing Feng, Zhou Lan, Rong Zhang, Alex W. Wessel, Sanjay Dhawan, Michael S. Diamond, Clark C. Chen, Robert J. Wechsler-Reya, Fred H. Gage, Hongzhen Hu, Jair L. Siqueira-Neto, Alysson R. Muotri, David A. Cheresh^STT

Cell. 2020 Feb 6;26(2):187-204.e10. doi: 10.1016/j.stem.2019.11.016. 
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Molecular profiling of cancer patients enables personalized combination therapy: the I-PREDICT study

Jason K. Sicklick ^STT, Shumei Kato ^STT, Ryosuke Okamura, Maria Schwaederle, Michael E. Hahn, Casey B. Williams, Pradip De, Amy Krie, David E. Piccioni, Vincent A. Miller, Jeffrey S. Ross, Adam Benson, Jennifer Webster, Philip J. Stephens, J. Jack Lee, Paul T. Fanta, Scott M. Lippman ^CCP, Brian Leyland-Jones & Razelle Kurzrock^STT

Nature Medicine. Volume 25, pages744–750(2019) 
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Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling

Junfeng Bi, Taka-Aki Ichu, Ciro Zanca, Huijun Yang, Wei Zhang, Yuchao Gu, Sudhir Chowdhry, Alex Reed, Shiro Ikegami, Kristen M Turner, Wenjing Zhang, Genaro R Villa, Sihan Wu, Oswald Quehenberger, William H Yong, Harley I Kornblum, Jeremy N Rich^STT, Timothy F Cloughesy, Webster K Cavenee, Frank B Furnari^CBS, Benjamin F Cravatt 2,Paul S Mischel^STT

Science Direct. Volume 30, Issue 3, 3 September 2019, Pages 525-538.e8 
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